Restricted
Therapy of gram negative infections including Pseudomonas, particularly in patients with Penicillin and Cephalosporin anaphylaxis or when there is no alternative susceptible agent.
Specialized nebulized form used in Cystic fibrosis patients (do not use IV formulation for nebulization).
Empiric therapy for Febrile neutropenia in patients with severe Penicillin and Cephalosporin allergy - must give in combination with Vancomycin (for the gram-positive coverage).
Monitor liver enzymes and renal function
No significant interactions.
Restricted to infectious diseases providers. Verify allergies and reactions to specific agents with patient before calling.
Antimicrobial class: Monobactam
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic