General Spectrum of Activity
Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.
Notable lack of gram positive activity versus other Cephalosporins.
Allergy (immediate and delayed).
Note potential cross-reactivity with aztreonam based on side chain.
Nonformulary agent. Available for cystic fibrosis patients and ocular injections.
Antimicrobial class: 3rd generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic