General Spectrum of Activity
Targeted therapy of resistant gram positive infections with MRSA and VRE including endovascular infection.
Creatine kinase weekly
Statins and fibrates - Increased myopathy. Monitor creatine kinase while on daptomycin therapy.
Higher doses used for endovascular infection.
Recommend Infectious Diseases Consult.
Inactivated by pulmonary surfactant and therefore insufficient for pulmonary infection.
Antimicrobial class: Cyclic Lipopeptide.
Pregnancy category: B
Average serum half life: 9 hours
CSF penetration: Possible - case reports
Lung penetration: Poor
Urine penetration: Therapeutic