General Spectrum of Activity
FDA warns against use in the following scenarios: uncomplicated urinary tract infection, acute bacterial exacerbation of chronic bronchitis, and acute bacterial sinusitis.
Monitor QTc in patients with increased risk
First Line Indications
Due to reduced Pseudomonas aeruginosa susceptibility to quinolones at Billings Clinic, double covering by adding a quinolone to cefepime/piperacillin-tazobactam is not recommended.
Antimicrobial class: Fluoroquinolone
Pregnancy category: C
Average serum half life: 7 hours
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic