Antimicrobials
Amoxicillin

Amoxicillin

Medium
Excellent
<$1/day

Spectrum of Activity

Dosing

General Information

Therapy of Streptococcal and Enterococcal infections as well as susceptible gram negative infections.

Commonly used for respiratory infections and urinary tract infections.

  •  Allergy/rash (immediate or delayed)
  •  Note EBV related rash
  •  Cytopenias

Allopurinol - increased rash

Good step down agent from IV ampicillin

Ampicillin susceptibility implies amoxicillin susceptibility

Oral amoxicillin has better tolerability and bioavailability than oral ampicillin

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Limited - use IV ampicillin for meningitis

Lung penetration: Therapeutic

Urine penetration: Therapeutic