Antimicrobials
Ampicillin

Ampicillin

Low
Low
See Below

Dosing

General Information

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria

IV: $10-15/day

PO: Nonformulary - prefer amoxicillin in most scenarios

Allergy and rash

EBV related rash (not allergy).

Rare: cytopenias, +ve Coombs.

Increased risk of rash with allopurinol.

Ampicillin susceptibility implies amoxicillin susceptibility.

Use amoxicillin for conversion to oral as appropriate. Oral amoxicillin has better bioavailability and less GI side effects than oral ampicillin.

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic