General Spectrum of Activity
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria
PO: Nonformulary - prefer amoxicillin in most scenarios
Allergy and rash
EBV related rash (not allergy).
Rare: cytopenias, +ve Coombs.
Increased risk of rash with allopurinol.
Ampicillin susceptibility implies amoxicillin susceptibility.
Use amoxicillin for conversion to oral as appropriate. Oral amoxicillin has better bioavailability and less GI side effects than oral ampicillin.
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic