Restricted
Therapy of serious, often nosocomial infections involving resistant gram negative organisms.
Valproic acid - Carbapenems decrease valproate levels and may decrease seizure threshold (cannot overcome this)
Restricted to Infectious Diseases (for very resistant organisms)
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 1 hour
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Therapeutic with high doses
Biliary penetration: Therapeutic