Nonpurulent (Streptococcal) cellulitis, necrotizing infections (cellulitis, fasciitis, Fournier's gangrene, pneumonia), and Streptococcal toxic shock syndromes can benefit from toxin inhibition by these adjunctive antibiotics. Clinical improvement is often shortened and length of hospitalization can be shortened.
Anti-toxin Antibiotic agents include:
There is evidence to suggest that even though a pathogen may demonstrate resistance on the susceptibilities, the anti-toxin activity can still have significant clinical effect.