Penicillin G Benzathine

Penicillin G Benzathine

$288 per 2.4 million units

Spectrum of Activity


General Information

  • Syphilis
  • Group A streptococcus pharyngitis
  • Secondary prophylaxis for rheumatic fever or glomerulonephritis
  • Pain at injection site
  • Jarisch-Herxheimer reaction
  • Hypersensitivity reaction

Note: appropriate formulation - not for intravenous use: cardiopulmonary arrest and death have occurred from inadvertent IV administration

Do NOT administer this formulation IV, intra-arterially or SubQ

Duration: 1-4 weeks (dose dependent)

Absorption: intramuscular - slow

Distribution: minimal in CSF

Time to peak serum concentation: 12-24 hours. serum levels are detectable for 1-4 weeks depending on dose

Excretion: excreted by renal tubular excretion, penicillin G is detected in urine for up to 12 weeks after single IM injection