Vancomycin Guideline
Vancomycin considerations

Vancomycin considerations


  • Vancomycin is a less effective choice than a beta-lactam antimicrobial for methicillin-susceptible staphylococcal (MSSA) infections.
  • Oral vancomycin administration is suitable only for C. difficile infection as it is not absorbed from the GI tract. Do not use oral vancomycin as stepdown therapy for IV vancomycin.
  • S. aureus with an MIC of greater than or equal to 2 mg/L has a high failure rate; consider an ID consult.