Clostridioides (Clostridium) difficile


Contact Precautions

General Information

Anaerobic spore forming gram positive bacilli, box-car shaped

  • Diarrhea often starts after taking antibiotics. Chemotherapy and malignancy also increase risk

  • Can occur in outbreaks

  • Recurrence is very common therefore previous history of C. difficile is a risk factor

  • Antacids, especially proton-pump inhibitors, may increase risk

  • Profuse, watery diarrhea: 3 or more bowel movements per day

  • Pseudomembranous colitis or toxic megacolon.

Do NOT perform test of cure, since test can remain positive even after cure

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