TMP-SMX 15mg TMP component/kg/day IV/PO divided q6h or q8h (renal dosing required)
Aerobic non-fermenting gram negative rod
May be acquired from diverse environmental sources (e.g. tap water).
Intubated patients or those with lung disease (bronchiectasis, cystic fibrosis) may be colonized.
Must distinguish colonization from clinically significant infection.
Most common reason for isolation is colonization of the respiratory tract.
Most common true infections:
Line-associated bloodstream infections
Hospital acquired pneumonia
May require contact precautions.
True pneumonia more likely in ICU and oncology patients, those with advanced age and after/during treatment with broad spectrum antimicrobial use.