Stenotrophomonas maltophilia

Stenotrophomonas maltophilia


See 'Additional Information'


General Information

TMP-SMX 15mg TMP component/kg/day IV/PO divided q6h or q8h (renal dosing required)

Aerobic non-fermenting gram negative rod

  • May be acquired from diverse environmental sources (e.g. tap water).
  • Intubated patients or those with lung disease (bronchiectasis, cystic fibrosis) may be colonized.
  • Must distinguish colonization from clinically significant infection.

Most common reason for isolation is colonization of the respiratory tract.

Most common true infections:

  • Line-associated bloodstream infections
  • Hospital acquired pneumonia

May require contact precautions.

True pneumonia more likely in ICU and oncology patients, those with advanced age and after/during treatment with broad spectrum antimicrobial use.