Candida non-albicans

Precautions

Standard Precautions

General Information

Caspofungin if C. glabrata or C. krusei; or critically ill

Fluconazole for non C. glabrata or C. krusei, not critically ill, and no recent fluconazole exposure

  • Voriconazole

  • Amphotericin B

Colonization and invasive infection in immunocompromised hosts especially in the setting of exposure to antifungal (i.e. fluconazole) and broad spectrum antimicrobials

Normally found in the GI tract and on skin. Often a colonizer when isolated from swabs or respiratory samples. Pneumonia due to Candida is extremely rare.

However, yeast should never be ignored or considered contaminants when isolated from blood cultures.

  • Candidemia

  • Line Infections

  • Endocarditis (rare- persistent blood cultures; risk factors for IE)

  • Endophthalmitis

  • Thrush

  • Esophagitis (check for HIV)

  • Vulvovaganitis

  • Hepatosplenic/Disseminated candidiasis

  • UTI (assoc. with stent or stone)

  • Ophthalmology should see if positive blood cultures

  • Repeat blood cultures every 48h until negative

  • Remove lines

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