Colonization and invasive infection in immunocompromised hosts especially in the setting of exposure to antifungal (i.e. fluconazole) and broad spectrum antimicrobials
Normally found in the GI tract and on skin. Often a colonizer when isolated from swabs or respiratory samples. Pneumonia due to Candida is extremely rare.
However, yeast should never be ignored or considered contaminants when isolated from blood cultures.