Penicillin VK

C difficile risk
Oral Bioavailability


300 - 600 mg PO q6 - 12h

600 mg PO q12h

No renal adjustment required

300 - 600 mg q6 - 12h

  • Give dose after dialysis on HD days

300 - 600 mg PO q6 - 12h

No data

General Information

  • Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract)

  • Prophylaxis after rheumatic fever

No significant interactions

Antimicrobial class: Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Lung penetration: Therapeutic

Urine penetration: Therapeutic

CSF penetration: None

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