Penicillin VK - Renal Dosing
In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.
If improving renal function, actual CrCl is likely higher than calculated CrCl.
If worsening renal function, actual CrCl is likely lower than calculated CrCl.
No renal adjustment required
300 - 600 mg q6 - 12h
- Give dose after dialysis on HD days
300 - 600 mg PO q6 - 12h