Vancomycin PO

C difficile risk
Oral Bioavailability


Defined criteria for use and/or important safety considerations. See below for more information.

125 mg PO QID

No renal adjustment required

General Information

C. difficile infection only, no oral absorption so not useful for other infections.

Do not use oral vancomycin as stepdown therapy for IV vancomycin

Systemic therapy

Possibility of accumulation in severe renal dysfunction.

No oral absorption.

May increase vancomycin resistant enterococci colonization in the gut.

Antimicrobial class: Glycopeptide

Pregnancy category: B

Average serum half life: 0 hours

Biliary penetration: None

Lung penetration: None

Urine penetration: None

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