Treatment of resistant Gram-negative infections when broad spectrum coverage is needed but not requiring anti-Pseudomonas or enterococcal activity
Treatment of polymicrobial diabetic foot infections when suspected bacteria have a high likelihood of resistance to cefazolin or ceftriaxone
Unlike other carbapenems, does not cover Pseudomonas.
No activity against enterococci or Stenotrophomonas
Valproic acid - Carbapenems decrease valproate levels and may decrease seizure threshold
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4 hours
Biliary penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic
CSF penetration: Insufficient data