Ertapenem

C difficile risk
Medium
Oral Bioavailability
N/A
Cost
$54/day

Dosing

Defined criteria for use and/or important safety considerations. See below for more information.

1 g IV q24h

CrCl >30 mL/minCrCl < 30 mL/minNo renal adjustment required 500 mg IV q24h

500 mg IV q24h

  • Give dose after dialysis on HD days

500 mg IV q24h

No Data

General Information

Treatment of resistant Gram-negative infections when broad spectrum coverage is needed but not requiring anti-Pseudomonas or enterococcal activity

Treatment of polymicrobial diabetic foot infections when suspected bacteria have a high likelihood of resistance to cefazolin or ceftriaxone

  • Unlike other carbapenems, does not cover Pseudomonas.

  • No activity against enterococci or Stenotrophomonas

Antimicrobial class: Carbapenem

Pregnancy category: B

Average serum half life: 4 hours

Biliary penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic

CSF penetration: Insufficient data

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