Defined criteria for use and/or important safety considerations. See below for more information.
1 g IV q24h
CrCl >30 mL/minCrCl < 30 mL/minNo renal adjustment required 500 mg IV q24h
500 mg IV q24h
Treatment of resistant Gram-negative infections when broad spectrum coverage is needed but not requiring anti-Pseudomonas or enterococcal activity
Treatment of polymicrobial diabetic foot infections when suspected bacteria have a high likelihood of resistance to cefazolin or ceftriaxone
Unlike other carbapenems, does not cover Pseudomonas.
No activity against enterococci or Stenotrophomonas
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4 hours
Biliary penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic
CSF penetration: Insufficient data