Spectrum Of Activity
Urinary tract infections, including urosepsis
Empiric therapy of severely ill patients with suspected Gram-negative infections (including Pseudomonas)
Synergy for some Gram-positive endocarditis infections
Does not cover Gram-positives or anaerobes
- Loop diuretics (e.g. furosemide)
Non-depolarizing muscle relaxants may be potentiated
Formal audiology assessment if planning to use aminoglycoside for >14d or if symptoms develop.
Inform patient of risk of ototoxicity and to report any symptoms.
Antimicrobial class: Aminoglycoside
Pregnancy category: D
Average serum half life: 2 hours
Biliary penetration: Moderate
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic