Cefoxitin

C difficile risk
Medium
Oral Bioavailability
N/A
Cost
$8/DAY

Dosing

Defined criteria for use and/or important safety considerations. See below for more information.

2 g IV q8h

2 g IV x 1 dose

CrCl > 50 mL/minCrCl 10 - 50 mL/minCrCl < 10 mL/minNo renal adjustment required2 g IV q8-12h2 g IV q24-48h

2 g IV q24-48h

  • Give dose after dialysis on HD days

1 g IV q24h

No data, consider 2 g IV q8-12h

General Information

  • Pelvic inflammatory disease (PID)

  • Single dose post-partum for 3rd and 4th degree tears

  • Surgical prophylaxis for gynecologic procedures

Does not cover Pseudomonas and other resistant Gram-negatives, ESBLs or AmpC producing Enterobacteriaceae

Drug Class: 2nd generation cephalosporin

CSF penetration: Insufficient data

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