Antimicrobials
Cefixime

Cefixime

Medium
Excellent
$

Spectrum of Activity

General Information

  • Uncomplicated anogenital gonorrhea infection (urethral, endocervical, vaginal, rectal) combine with azithromycin 1 g PO in a single dose
  • May be considered for empiric therapy for outpatient pyelonephritis and hemodynamically stable patients with complicated urinary tract infections
  • Can be used for other infections resistant to first line agents but susceptible to cefixime

Any gonorrhea infection in men who have sex with men OR pharyngeal infection in men or women, preferred therapy is:

  • Ceftriaxone 250 mg IM PLUS azithromycin 1 g PO in a single dose

Potential link to seizure risk

Potential link to seizure risk

Drug Class: 3rd generation cephalosporin

CSF penetration: Insufficient data