Antimicrobials
cefepime

cefepime

C difficile risk
High
Oral Bioavailability
N/A
Cost
$85/day

Dosing

Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.

General Information

Empiric Therapy for Febrile Neutropenia in patients who have a penicillin allergy or who are clearing methotrexate

Allergy (immediate or delayed), eosinophilia, thrombocytopenia, neutropenia Transient liver function test increase, diarrhea

Antimicrobial class: Parenteral cephalosporin 4th generation

Average serum half life: 1.7 hours

Route of Elimination: Renal clearance (60 % unchanged)