Antimicrobials
Erythromycin

Erythromycin

None
Moderate

General Information

Pertussis, Chlamydial infections, mycobacterial infections, latency in pregnancy

Monitor QTc in patients with increased risk.

  • GI upset, diarrhea
  • Prolongation of QTc interval

Substrate of CYP3A4. Multiple CYP450 interactions possible - consult a pharmacist for more detail.

May increase digoxin, carbamazepine level. Caution with QTc prolonging medications

Not available

  • 333 mg capsule
  • Tablets and capsules are preferred especially over an unpleasant tasting liquid.
  • Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary

Erythromycin use has been associated with an increased risk of hypertrophic pyloric stenosis in term infants less than 14 days of age.

Antimicrobial class: Macrolide

Route of Elimination: Primarily hepatic