Antimicrobials
cefUROXime

cefUROXime

C difficile risk
Medium
Oral Bioavailability
Excellent
Cost
IV-15$

Dosing

Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.

General Information

Community acquired lower respiratory tract infections.

  • Allergy (immediate & delayed)

  • Positive Coombs

  • Cytopenias

  • GI upset, diarrhea

  • Abnormal liver enzymes

Antimicrobial class: 2nd Generation Cephalosporin

Average serum half life: Pediatrics: 1.4-1.9 hours.

Route of Elimination: 66-100% as unchanged drug in urine by both glomerular filtration and tubular secretion