Neonatal HSV

Neonatal Symptoms

  • Check skin, eye including conjunctivitis and mucous membranes for lesions

  • CNS involvement or encephalitis and may have vesicular skin lesions

  • May involve multiple organ systems such as lungs, liver, adrenal glands, CNS and can have vesicular skin lesions

  • Consider HSV in neonates with sepsis syndrome or disproportionate liver dysfunction

  • Consider if no improvement on antibiotics for >24 hrs

  • Consider HSV in neonates with fever, irritability, abnormal CDF findings, thrombocytopenia and seizures

  • Normal CSF cell count and biochemical parameters do not exclude neonatal HSC CNS infection

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