Prosthetic Joint Infections (PJIs)
P. acnes

P. acnes

Duration of Therapy

Prosthesis Retained: 4-6 weeks IV or highly bioavailable (e.g. Ciprofloxacin when no contraindication)

Amputation: Pathogen-specific antimicrobial therapy should be given until 24–48 hours after amputation assuming all infected bone and soft tissue has been surgically removed and there is no concomitant sepsis syndrome or bacteremia