Prosthetic Joint Infections (PJIs)
MRSA

MRSA

Treatment

If Retain Prosthesis or 1-Stage Exchange, ADD

Definition

Prosthesis Retained: 2-6 weeks IV + rifampin followed by 3–6-week months oral agent + rifampin

Amputation: Pathogen-specific antimicrobial therapy should be given until 24-48 hours after amputation assuming all infected bone and soft tissue has been surgically removed and there is no concomitant sepsis syndrome or bacteremia