Febrile Neutropenia - Adult

Febrile Neutropenia - Adult

Clinical Considerations

  • Absolute neutrophil count ≤ 500
  • Temperature ≥ 100.4°F (38.3°C) for 30 min or > 101°F (38.0°C) sustained over 1 hr
  • Delayed recovery of T cell, CD8 T cell, B cell, neutrophil and lymphocytes
  • Damaged mucosal membranes
  • Central lines
  • Central lines
  • GVHD
  • Steroids
  • Immune suppression drugs
  • Graft type
  • T cell depletion

More Information

Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA, Raad II, Rolston KV, Young JA, Wingard JR; Infectious Diseases Society of America. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2011 Feb 15;52(4):e56-93. doi: 10.1093/cid/cir073. PMID: 21258094.