IV antibiotics should only be used if the patient cannot tolerate PO
Procalcitonin can be useful in determining which patients are least likely to benefit from abx and for which abx can SAFELY be discontinued (esp. for mild-moderate AECOPD)
Risk Factors for Pseudomonas and Enterobacteriaceae:
Severe exacerbation defined as:
Risk Factors for Pseudomonas and Enterobacteriaceae: