Mild infection:
Moderate to severe disease:
initiate TMP/SMX and add a second agent (e.g. Minocycline, Levofloxacin) if there is a delay in clinical improvement with monotherapy
Mild infection:
Moderate to severe disease:
Aerobic, non-fermenting, gram-negative rod
May be acquired from diverse environmental sources (e.g. tap water)
Colonization may occur in patients with structural lung disease
Must distinguish colonization from clinically significant infection
Most common: