Firstline - Clinical Decisions

Negative Results

Consider discontinuing unnecessary coverage

Sensitivity
- S. pneumo, H. influenzae, E. coli K1 = 100%
- CMV, HSV 1 and 2, VZV, HPeV = 100%
- EV = 95.7% and HHV-6 = 85.7%
- Cryptococcus neoformans/gattii = 100%
Specificity = 99.2-100%
Less altered by anti-infective use than culture