Piperacillin-Tazobactam 4.5g IV q6h
with or without
Vancomycin IV
OR
Cefepime 1g IV q6h
PLUS
Metronidazole 500mg IV q12h
Aztreonam 1g IV q8h
Vancomycin
Treatment of infection should be limited to 4-7 days unless it is difficult to achieve adequate source control (longer treatment has not been associated with improved outcome)