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Guidelines
Surgical Prophylaxis Dosing

Surgical Prophylaxis Dosing

Dosing

  • Dose: 2 g
  • If >120 kg: 3 g
  • Re-dosing intra-op: q4h
  • Dosing post-op: q8h
  • Dose: 2 g
  • If >80 kg: 2 g
  • Re-dosing intra-op: q2h
  • Dosing post-op: q6h
  • Dose: 600 mg
  • If >80 kg: 900 mg
  • Re-dosing intra-op: q6h
  • Dosing post-op: q8h
  • Dose: 500 mg
  • If >80 kg: 500 mg
  • Re-dosing intra-op: q6h
  • Dosing post-op: q8h
  • Dose: 400 mg
  • If >80 kg: 400 mg
  • Re-dosing intra-op: q8h
  • Dosing post-op: q12h
  • Dose:
    • Preferred: 5 mg/kg IV once
    • 80 mg
  • If >80 kg:
    • Preferred: 5 mg/kg IV once
    • 100 mg
  • Re-dosing intra-op:
    • 5 mg/kg IV once: None (lasts 24+ hrs)
    • 80 or 100 mg: q4h x 1
  • Dosing post-op:
    • 5 mg/kg IV once: None (lasts 24+ hrs)
    • 80 or 100 mg: q8h x 1
  • Dose:
    • 50-69 kg: 1 g
    • 70-100 kg: 1.5 g
    • 101-135 kg: 2 g
    • 136-165 kg: 2.5 g
  • Re-dosing intra-op: q12h (ask Pharmacy to dose if renal disease or elderly)
  • Dosing post-op: q12h (ask Pharmacy to dose if renal disease or elderly)