Firstline - Clinical Decisions

Guidelines

Uncomplicated Acute Cystitis

Inclusion Criteria

Female
No stones
No catheter
No urologic abnormality

Empiric Treatment

Nitrofurantoin 100mg PO bid x 5 days

OR

Fosfomycin 3g PO once

Option for ESBL E. coli or VRE
Does not cover Klebsiella spp

OR

Trim/Sulfa DS 1 tab PO bid x 3 days

OR

Cephalexin 500mg PO TID x 7 days

Note

Reserve Cipro for more serious UTIs, such as pyelonephritis