Ceftriaxone 2g IV q24h
PLUS
Azithromycin 500mg IV q24h
OR
Levofloxacin 750mg IV daily
Ampicillin/Sulbactam 3g IV q6h
Azithromycin 500mg IV daily
5 days of therapy for most patients is non-inferior to 7-14 days
7 days of therapy for moderate immunocompromised or SLD
10-14 days if poor clinical response or immunocompromised/SLD
Consider the Procalcitonin Pathway