Cefepime 1g IV q6hr
OR
Zosyn 4.5g IV q8hr
PLUS
Azithromycin 500mg IV/PO q24h x 3 days
Doxycycline 100mg IV/PO q12h x 5 days
ADD Vancomycin PTD
5 days of therapy for most patients is non-inferior to 7-14 days
7 days of therapy for moderate immunocompromised or SLD
10-14 days if poor clinical response or immunocompromised/SLD
Consider the Procalcitonin Pathway
Guidelines