• Vancomycin
• Linezolid
• TMP/SMX
• Cefepime
• Piperacillin/tazobactam or Ampicillin/sulbactam

Gram-positive cocci in clusters, coagulase-positive

Staphylococcus aureus is a ubiquitous organism that colonizes the skin/nares and can cause invasive disease

• Purulent ABSSSIs

• Bacteremia (Infectious Diseases consultation recommended)

• CLABSIs

• Osteomyelitis

• Endocarditis

• Pneumonia

• Meningitis (post-operative, TBIs)

• Infection of prosthetic devices (e.g. heart valves, prosthetic joints)