Penicillin G +/- Clindamycin
Anaerobic spore forming gram positive bacilli, box-car shaped
Environmental (soil, water) organism as well as human/animal digestive tract
Associated with penetrating wounds with environmental exposure
Gas gangrene/Clostridial myonecrosis
Necrotizing skin and soft tissue infection
Septic abortion, tubo-ovarian abscesses, uterine gas gangrene
Intra-abdominal abscess
Fatal bacteremia with massive exotoxin-mediated hemolysis
Foodborne self-limited gastrointestinal illness
Surgical debridement of devitalized tissue crucial