Antimicrobials
Fosfomycin

Fosfomycin

Low
Low (20 to 40%)
$84-89/dose

Spectrum of Activity

Dosing

General Information

Cystitis caused by E.coli or VRE

Hypersensitivity

  • Diarrhea

  • Headache

  • Hypersensitivity

  • Absorption: Rapidly absorbed
  • Distribution (Vd): 90 to 180 L
  • Protein Binding: None
  • Bioavailability: 
    • Fasting: 37%
    • With food: 30%
  • Half-Life: 
    • 3 to 8 hours
    • CrCl <54 mL/minute: 50 hours
    • Hemodialysis patients: 40 hours
  • Excretion: 
    • Urine (38% as unchanged drug)
    • Feces (18% as unchanged drug)