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Antimicrobials
Fidaxomicin

Fidaxomicin

Restricted

None
Poor (Less than 20%)
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Spectrum of Activity

General Spectrum of Activity
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General Information

C. difficile infection

  • Assess for effectiveness of treatment

  • Assess for hypersensitivity

  • Nausea

  • Hypersensitivity

  • Fever

Approximately $3800-4200 per course (#20 tablets)

  • Absorption: Oral: Minimal systemic absorption
  • Distribution: Largely confined to the gastrointestinal tract
  • Metabolism: Intestinal hydrolysis to less active metabolite (OP-1118)
  • Excretion: 
    • Feces (>92% as unchanged drug and metabolites)
    • Urine (<1% as metabolite)