Cefazolin
Renal

Renal

Not On Dialysis

CrCl ≥35 mL/min

No adjustment needed

CrCl 11-34 mL/min

2 g IV q12h

CrCl ≤10 mL/min

2 g IV q24h

HD

Standard HD Dose

1 g IV q24h

PD

500 mg IV q12h

CVVHD

1 L/h Dialysate Flow Rate

2g q12h

2 L/h Dialysate Flow Rate

2g q12h

3-4 L/h Dialysate Flow Rate

2 g q8h