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Antimicrobials
Amoxicillin/Clavulanate

Amoxicillin/Clavulanate

Medium
Moderate (40 to 70%)
$ (<$25/day)

Spectrum of Activity

General Spectrum of Activity
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Dosing

General Information

  • Allergic reactions

  • Renal function

  • LFTs

  • Allergic reactions

  • Diarrhea, nausea, vomiting

  • Drug-induced liver injury

Augmentin

Amoxicillin:

  • See individual amoxicillin monograph

Clavulanic Acid:

  • Protein Binding: ~25%
  • Half-Life Elimination: 1 hour
  • Time to Peak: 1.5 hours
  • Excretion: Urine (25% to 40% as unchanged drug)