Staphylococcus aureus Bacteremia


Initial Empiric Treatment

Vancomycin 25-30 mg/kg loading dose

Further dosing depends on renal function

Duration of Therapy

  • Infective endocarditis has been excluded
  • No implanted prostheses are present
  • Follow up blood cultures drawn 2-4 days after the initial set are sterile
  • The patient defervesces within 72 hours of initiation of effective antibiotic therapy
  • No evidence of metastatic infection is present on examination

Longer treatment duration is needed for patients who have complicated Staphylococcus aureus bacteremia. Strongly consider consultation with Infectious Diseases.