Cellulitis - Non-purulent
Non-purulent Cellulitis Treatment

Non-purulent Cellulitis Treatment

Notes

Look for and manage predisposing factors, such as underlying venous stasis, tinea pedis. Consider consultation with Wound Care when appropriate.

Remember that it often takes at least 48 hours before improvements are seen in erythema/edema.

Duration of Therapy

5 days depending upon clinical response

Suggested Regimen

Oral Treatment

OR

IV Treatment

Consider IV treatment for patients with systemic signs of infection or who cannot tolerate oral therapy.

Consider Infectious Diseases consultation in patients who are immunocompromised, history of penetrating injury, recent freshwater or saltwater exposure or with severe skin and soft tissue infections, to assist with empiric antimicrobial therapy.

Penicillin Anaphylaxis

Oral Treatment

OR

IV Treatment

Vancomycin dosing as per nomogram

Consider using IV vancomycin in patients who are systemically unwell and cannot tolerate oral therapy.

Consider Infectious Diseases consultation in patients who are immunocompromised, history of penetrating injury, recent freshwater or saltwater exposure or with severe skin and soft tissue infections, to assist with empiric antimicrobial therapy.

Reassess Therapy on Day 3