General Spectrum of Activity
Uncomplicated cystitis in females with normal renal function
Interstitial pneumonitis and fibrosis especially with prolonged use.
Antacids decrease absorption
Antimicrobial class: Nitrofuran
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: None
CSF penetration: None
Lung penetration: None
Urine penetration: Therapeutic
Think of this drug as a urinary antiseptic.
Caution - not indicated for treatment of pyelonephritis
Not recommended in males due to inadequate tissue penetration, especially with possible occult prostatitis.