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Antimicrobials
Doxycycline

Doxycycline

Low
Excellent

Dosing

General Information

  • Skin and soft tissue infection (due to MRSA)
  • Community acquired pneumonia
  • Malaria prophylaxis
  • Zoonoses
  • GI upset and erosive esophagitis
  • Photosensitivity rash
  • Teeth staining
  • Divalent cations - decreased absorption
  • Increased digoxin levels
  • Increased INR with warfarin
  • Some anticonvulsants can decrease doxycycline levels

Antimicrobial class: Tetracycline

Pregnancy category: D

Average serum half life: 18 hours

Urine penetration: Poor

Lung penetration: Therapeutic

CSF penetration: Poor

Biliary penetration: Therapeutic