Cefotaxime is commonly used in the treatment of bacterial meningitis, community-acquired pneumonia and intra-abdominal infections.
The spectrum of activity of cefotaxime is similar to that of ceftriaxone but requires multiple daily dosing and renal adjustment. Consider using ceftriaxone as an alternative.
Antimicrobial class: 3rd Generation Cephalosporin
Pregnancy category: B
Average serum half life: 1.5 hours
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic
The spectrum of activity of cefotaxime is similar to that of ceftriaxone but requires multiple daily dosing and renal adjustment. Consider using ceftriaxone as an alternative.