In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.
If worsening renal function, actual GFR is likely lower than calculated.
If improving renal function, actual GFR is likely higher than calculated eGFR.
Intermittent Dialysis
No dose adjustment recommended
Use must be approved by Infectious Diseases
Continuous Dialysis
Amphotericin B - liposomal and lipid complex (Ambisome and Abelcet) - 3-5mg/kg IV daily.
Use must be approved by Infectious Diseases.
Discuss dosing with Pharmacy
Amphotericin B - Lipid Associated