Antimicrobials
Ceftolozane-Tazobactam

Ceftolozane-Tazobactam

Restricted

High
N/A
$$$$$

Spectrum of Activity

Dosing

General Information

Reserve use for patients with multidrug-resistant gram-negative organisms (eg, extensively drug-resistant P. aeruginosa) with limited treatment options.

Renal function.

  • GI side effects
  • Hypersensitivity reaction

ID Consult Required.

For treatment of MDR gram negative organisms, administer infusion over 3 hours.

Antimicrobial class: Cephalosporin combination

Average serum half life: 4 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

Biliary penetration: Therapeutic